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Health & Body

The Zoom In: Prostaglandins

An overview of what prostaglandins are and how they’re linked to the menstrual cycle.

3 min read | October 19, 2021

You’d be forgiven for not knowing what a prostaglandin is; it’s a term that tends to be left out of our day-to-day period-related vocab. Yet prostaglandins are really important because they can influence things including inflammation and blood flow, and are involved in various reproductive processes. 

They’re hormone-like compounds that have many roles in the body and are produced wherever they're needed. In the uterine lining, they’re produced from the endometrium as progesterone levels drop at the end of each menstrual cycle. This helps the uterus contract to shed its lining.

In the menstrual cycle, prostaglandins play an important role in the series of events that lead up to your period (the event we refer to as menstruation). This includes helping your uterine muscles contract, constricting uterine blood vessels, and encouraging healthy inflammation. (PSA: not all inflammation is bad - it's an important part of lots of your body's healthy processes).

So if you’re thinking prostaglandins are the reason you get period pain, that’s probably not entirely correct. An excess of prostaglandins in your uterus is likely what causes period pain, not the prostaglandins themselves. What does “excess” really mean, and why exactly does it happen? To know this, we’ll need to wait for science to catch up...

About Author

Your hormones can be complex and unpredictable. That’s why we’re here, on The Regular, to do what’s long overdue - to demystify what’s going on with our reproductive systems, our hormones and our whole cycle.

We’re here to support your day-to-day queries serving useful content that is uncomplicated and unbiased. No topic is too complicated or too specific for us to address/focus on.

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We recognize that every body is complex and everyone's symptoms are different so we’re actively working hard to provide additional solutions.

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